Abstract

# {#article-title-2} Trampe et al.1 should be commended for their investigation into the rate of seropositivity of the anti-JC virus (JCV) antibodies in a German multiple sclerosis (MS) cohort treated with natalizumab. Further points need to be considered. Trampe et al.1 investigated the rate of anti-JCV antibodies by using a confirmatory 2-step ELISA on 2,782 blood samples. Although the serum sample is a good option for the detection of anti-JCV antibodies by ELISA method, it would be more accurate if they measured JVC-DNA in the urine samples of …

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