Abstract
The article discusses the choice of anticoagulant therapy in patients with atrial fibrillation and a number of concomitant diseases – coronary heart disease, including after percutaneous coronary interventions, diabetes mellitus, chronic kidney disease, chronic obstructive pulmonary disease, and in the elderly. The data of subanalyses of a randomized clinical trial of ARISTOTLE are presented, indicating a high profile of efficacy and safety of the new oral anticoagulant apixaban in this category of patients.
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