Abstract
Helicobacter pylori (H. pylori) infection is tightly associated with gastrointestinal disorders such as chronic gastritis, peptic ulcer, gastric MALToma, and gastric cancer. Decreased antibiotic susceptibility in H. pylori is a worldwide problem. Our objective was to determine in vitro antimicrobial susceptibility of H. pylori isolates obtained from gastric mucosa biopsies of children with H. pylori-associated gastroduodenal diseases using disk-diffusion method. A total 76 biopsy specimens were studied; antibiotic susceptibility was assessed in case of 30 children in whom H. pylori was revealed by bacteriology. The maximum resistance of H. pylori isolates was revealed to clarithromycin with nine resistant isolates (30.0%). The rate of resistance to metronidazole, amoxicillin, furazolidone, tetracycline, and levofloxacin was 23.3, 33.3, 16.7, 25.0, and 16.7%, respectively. Multidrug resistance was detected in 20.0% of H. pylori strains. The high prevalence of resistance to antibiotics used in eradication therapy is becoming a problem which needs eradication therapy regimen use based on regional H. pylori resistance rates.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
