ANTIBIOTIC PROPHYLAXIS USE IN PATIENTS ADMITTED IN GENERAL SURGERY DEPARTMENT AT A TERTIARY CARE TEACHING HOSPITAL IN HARYANA

Abstract

Objective: In India, due to a lack of adequate information and guidelines for antimicrobial prophylaxis in surgery, there is a need to generate baseline data on the pattern of the use of prophylactic antibiotics. Hence, we planned this study with an objective to study the antimicrobial prophylaxis use in the patients admitted to the general surgery department. Methods: The present study was a prospective observational study conducted in the department of pharmacology in collaboration with the department of surgery with the prior approval of the Institutional Ethical committee. All data were retrieved from the patients’ case records. Using a convenient sampling method, 100 adult patients who underwent surgical procedures in MMIMSR during the study period were taken. Results: A total of 100 patients admitted to the general surgery department of MMIMSR fulfilling the inclusion and exclusion criteria were enrolled. Out of 100 patients, 52 (52%) were male and 48 (48%) were female patients who underwent surgery and the majority of the patients enrolled are between 48 and 58 years (40%) of age. Cholecystectomy (28%) was the most frequent performed surgery type followed by hernial repair (24%) and hemorrhoidectomy (14%) Among all cases, surgical antibiotic prophylaxis was recommended in 93 (93%) patients. The most preferred route of administration of surgical antibiotic prophylaxis was parenteral route 100 (100%) and ceftriaxone was most commonly prophylactically prescribed antibiotic. Conclusion: Surgical site infection is the most common nosocomial infections in surgical patients accounting for prolonged hospital stay, mortality, and increased cost of care. According to the analyzed results of our study and from view of literature, the present study provides us patterns of antibiotic usage in patients admitted in surgery wards.