Abstract
Pseudomonas aeruginosa is an adaptable bacteria causing an extensive spectrum of infections and intrinsically resistant to many antibiotics. As antimicrobial resistance has increased due to many resistance mechanisms. This study was done to evaluate the antibiogram of Pseudomonas aeruginosa at a tertiary care centre. Thirty seven isolates were recovered from various specimens for a period of 6 months from June to December 2020 and the disc diffusion method was used for antibiotic susceptibility testing as per CLSI guidelines. Pseudomonas aeruginosa was found to be high (45.9%) in pus/wound than other samples. Antibiotic resistance rate of the isolates were 29.7% to ceftazidime, 16.2% to Piperacillin-tazobactam, 27 % to gentamicin and ciprofloxacin, 16.2% to tobramycin and imipenem, 24.3% to meropenem, 27% to ciprofloxacin, 13.5% to aztreonam, 21.6% to amikacin, 24.3% to cefepime and levofloxacin, 21.6 to tigecycline. All strains were sensitive to colistin. 27% of the organism were found to be multidrug resistance. Hence periodic susceptibility testing can curb the resurgence of these bacterial pathogens.
Highlights
Pseudomonas aeruginosa (P. aeruginosa) is an opportunistic bacteria which causes a extensive spectrum of infections ranging from ear infections, bacteremia, urinary tract infections, burn infections, bacteremia and respiratory tract infections.[1,2] Prevalence rate of P. aeruginosa infection ranges from 10-30% in India.[3]
Pseudomonas aeruginosa is an adaptable bacteria causing an extensive spectrum of infections and intrinsically resistant to many antibiotics
Thirty seven isolates were recovered from various specimens for a period of 6 months from June to December 2020 and the disc diffusion method was used for antibiotic susceptibility testing as per CLSI guidelines
Summary
Pseudomonas aeruginosa (P. aeruginosa) is an opportunistic bacteria which causes a extensive spectrum of infections ranging from ear infections, bacteremia, urinary tract infections, burn infections, bacteremia and respiratory tract infections.[1,2] Prevalence rate of P. aeruginosa infection ranges from 10-30% in India.[3] It causes both hospitalized and community acquired infections. P. aeruginosa infection pose a therapeutic challenge as the organism has both intrinsic and acquired resistance to various classes of antibiotics. As antibiotic resistance is increasing drastically among the P. aeruginosa which is a threat to the Public health. Monitoring these bacterial populations is necessary to formulate the antibiotic treatment policy. This analysis was done to assess the antibiotic profile of P. aeruginosa isolates from different specimens
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