Abstract
This chapter discusses the side effects of antibacterial and antiviral drugs. No new side effects are described with nitrofurantoin derivatives during the past year but an increasing number of well documented studies on the chronic pulmonary syndrome are published. Six cases of severe contact dermatitis are reported from prolonged or repeated courses of topical idoxuridine. Adenine and cytosine arabinoside (vidarabine and cytarabine) are agents that interfere with the synthesis of DNA and that are used against the DNA viruses. However, they damage rapidly growing human tissue and are, therefore, especially dangerous in the newborn. Adenine arabinoside can be used intravenously to treat uveal herpes virus infections at a tolerated dose but fail to produce a clinical response in toxic doses in patients with cytomegalovirus infections following renal transplant. Ribavirin is a synthetic agent interfering with the synthesis of both RNA and DNA, and no adverse reactions are observed. Effects on urea, cholesterol, creatinine, alkaline phosphatase or the hematological parameters have not been examined so far.
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