Abstract
The present study was aimed to manifest the antibacterial and antifungal activity of methanolic extracts of Salix alba L. against seven Gram-positive and Gram-negative bacterial pathogens e.g. Streptococcus pyogenes, Staphylococcus aureus (1), S. aureus (2), Shigella sonnei, Escherichia coli (1), E. coli (2) and Neisseria gonorrhoeae and three fungal isolates from the air such as Aspergillus terreus, A. ornatus, and Rhizopus stolonifer. Two different serotypes of S. aureus and E. coli were used. The agar well-diffusion method results showed the dose-dependent response of plant extracts against bacterial and fungal strains while some organisms were found resistant e.g. E. coli (1), S. sonnei, A. terreus and R. stolonifer. The highest antibacterial activity was recorded at 17.000±1.732 mm from 100 mg/mL of leaves methanolic extracts against S. pyogenes while the activity of most of the pathogens decreased after 24 h of incubation. The highest antifungal activity was reported at 11.833±1.0 mm against A. ornatus at 50 mg/mL after 48 h of the incubation period. These experimental findings endorse the use of S. alba in ethnopharmacological formulations and suggest the use of methanolic extracts of the said plant to develop drugs to control the proliferation of resistant disease causing pathogenic microbes.
Highlights
The plants represent themselves as a treasury of natural therapeutic compounds and are pronounced as ‘Medicinal Plants’ that are well renowned for having anti-infectious properties and are used for the treatment of almost all kinds of ailments like skin, respiratory, reproductive, digestive disorders, chickenpox, dysentery, fever, hysteria, malaria, abdominal pain, mania, infantum, tonsillitis, and vomiting
The antibacterial activity of the leaves and the stem bark extracts of S. alba was assessed at 75 mg/mL
The comparison with the standard antibiotic revealed that the highest activity in terms of activity index (AI) and percent activity (PA), was observed against the N. gonorrhoeae (AI = 1.15 and Percentage Activity (PA) = 115) followed by S. aureus (1) (AI = 0.95 and PA = 95)
Summary
The plants represent themselves as a treasury of natural therapeutic compounds and are pronounced as ‘Medicinal Plants’ that are well renowned for having anti-infectious properties and are used for the treatment of almost all kinds of ailments like skin, respiratory, reproductive, digestive disorders, chickenpox, dysentery, fever, hysteria, malaria, abdominal pain, mania, infantum, tonsillitis, and vomiting. Babylonian, Egyptian, Assyrian, Chinese, Greek, and Roman civilizations used Willow for relieving pain and inflammation. S. alba is commonly known as Willow, White Willow, Silver Willow, and Golden Willow. It belongs to the genus Salix and the family Salicaceae. Salicylic acid is a glycoside in nature and is found to be responsible for all pain-relieving actions of S. alba (Sulima and Przyborowski, 2019)
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Schedule a callMore From: Brazilian journal of biology = Revista brasleira de biologia
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