Abstract
Antibacterial Activities of Cationic Porphyrins and Porphyrin Encapsulated Gold Nanorods on Bacterial Cell Lines
Highlights
Diseases caused by bacteria, parasites and fungi have become a major problem globally, this is despite the exceptional advances in medicine that have been reported far 1-3
The bacterial strains used for this study included the Gram-positive bacteria, E. faecalis (ATCC#29212), S. aureus (ATCC# 25925) and the Gram-negative bacteria K. pneumonia (ATCC#4352) obtained from the microbiology culture bank at the University of Zululand where all the microbiological tests were carried out
The band at 2976-1 is the N-H out of phase and is more significant in the porphyrin synthesized in an ionic liquid than in propionic acid
Summary
Parasites and fungi have become a major problem globally, this is despite the exceptional advances in medicine that have been reported far 1-3. The impact of these diseases is very panoptical in developing and underdeveloped countries due to the lack of modern medicine in these countries. Reports have shown the use of cationic porphyrins to dominate anionic or neutral porphyrins in terms of antimicrobial activity . 17-21 The addition of a central metal atom in the porphyrin structure improves the porphyrin polarity and lipophilicity 22.
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