Abstract
Essential oils possess antiaging properties due to their antioxidant activity. This study aims to determine the antiaging activities of four main Indonesian essential oils and their irritation potential on the skin. The spot yeast and in vivo rat skin with UVB exposure methods were used to analyze the antiaging activity of essential oils on aging triggered by endogenous and exogenous factors, respectively. Meanwhile, patch tests and clinical evaluations were used for the skin irritation potential analysis. The antiaging activity results from the endogenous factor showed that the use of clove, patchouli, nutmeg, and citronella oils increased yeast viability at concentrations of 20, 40, 60, and 100 µg/mL, respectively. Furthermore, nutmeg, cloves, citronella, and patchouli oils decreased the wrinkle score on rat skin after UVB exposure (exogenous factor). The skin irritation potential results of patchouli, nutmeg, citronella, and clove oils were none (0), slightly (0.02), moderately (0.09), and very irritating (0.39), respectively.
Highlights
The process of aging is a physical change and functional phenomenon that occurs with time or environmental effects, appearing at all organism levels [1]
This study shows that introducing active materials of essential oil can affect the density of yeast colonies compared with the control (+dimethyl sulfoxide (DMSO))
The amount of antiaging activity depends on their chemical components
Summary
The process of aging is a physical change and functional phenomenon that occurs with time or environmental effects, appearing at all organism levels [1]. According to Ganceviciene et al [2], aging skin is affected by endogenous factors (intrinsic aging) and exogenous factors (extrinsic aging). This intrinsic aging occurs naturally from prolonged physical changes. Extrinsic aging is affected by external variables, such as solar exposure, smoking, and other lifestyle factors [3]. This process has been defined as a major and important aspect of skin health. These products are used to acquire smooth, soft, free, and transparent skin [2]
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