Abstract

The presently ongoing pandemic of human SARS‐CoV‐2 infections (COVID‐19) presents an enormous challenge in surveillance, vaccine and antiviral drug development. Here we report the synthesis of new bioactive quinoline‐morpholine hybrid compounds and their virological evaluation, which proves pronounced cell culture‐based inhibitory profile against SARS‐CoV‐2. Thus, selected quinoline compounds may suggest specific hit‐to‐lead development.

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