Abstract

THE FEMALE PROSTATE, homologue of the male ventral prostate, is present in some female rats. The incidence varies in different strains and may be increased by inbreeding (1). Price (2) demonstrated that during a limited period in the immature female rat (2,1 to 40 days of age) these prostates exhibit evidence of andrc-genie stimulation. In a previous report (3) we confirmed this finding. Included in this report were a few cases of castrate immature females which also had prostates show-ing some androgenic stimulation. This finding was indicative evidence for the hypo-thesis advanced by Price, that the female adrenal cortex might have a temporary an-dromimetic function such as has been demonstrated by us in the immature male rat (4,5). The present report concerns further investigation on this matter, specifically the respective roles of the immature ovary and adrenal in the production of the andro-genie substances responsible for stimulation of the immature female prostate.

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