Abstract
It was not until the vomiting centre itself was correctly localized in the bulbar reticular formation that the idea of a separate chemosensory station could be formulated (Borison and Wang 1953). Figure 1 shows where the vomiting centre was thought to be located before 1949 (panel A) and then where it was mapped by Borison and Wang (1949) (panel B). Earlier workers (Hatcher and Weiss 1923) simply assumed that the vomiting centre was inherently responsive to “centrally-acting” emetic drugs applied locally to the ala cinerea on the brain surface; whereas, we used direct electrical stimulation to activate the centre in the parenchymal reticular formation. Indeed, there is at present no neuropharmacological basis for attributing any functional chemoselectivity to the particular medullary neurons that comprise the vomiting centre.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
