Abstract
Photoplethysmography (PPG) is a technique that permits noninvasive measurement of changes in the volume of tissues. A novel device uses PPG to assess changes in duodenal mucosal perfusion. When tested in septic piglets, data obtained using this device correlate with the blood lactate concentration and duodenal serosal microvascular blood flow as measured with a laser Doppler flowmeter. This new PPG-based approach for continuously monitoring gut mucosal perfusion warrants further development, leading to prospective clinical trials in patients.
Highlights
Photoplethysmography (PPG) is a technique that permits noninvasive measurement of changes in the volume of tissues
Some of the animals were infused with a suspension of viable Pseudomonas aeruginosa to induce septic shock; the remaining animals were not challenged with the Gram-negative bacteria preparation
Light-emitting diodes provide the light in present-day commercially available devices that employ PPG for medical applications, such as beat-to-beat monitoring of blood pressure
Summary
Photoplethysmography (PPG) is a technique that permits noninvasive measurement of changes in the volume of tissues. In the previous issue of Critical Care, Jacquet-Lagrèze and colleagues from several institutions in Lyon, France, report results from a preclinical study of a novel perfusion monitoring device [1]. The novel monitoring device was developed by Advanced Perfusion Diagnostics [2], a biotechnology start-up company in Lyon.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
