Abstract
This work evaluates the vectorcardiographic dynamic changes in ischemic patients before and during Percutaneous Transluminal Coronary Angioplasty (PTCA). Four vectorcardiographic parameters were computed in 51 ischemic and 52 healthy subjects with the objective of assessing the differences between both groups: ST Vector Magnitude Area (STVMa), T Vector Magnitude Area (TVMa), ST Vector Difference (STVD), and T Vector Difference (TVD). The conventional ST-Change Vector Magnitude (STCVM) and Spatial Ventricular Gradient (SVG) were also calculated. Results indicate that the most of them show significant differences between healthy and ischemic subjects. Since, the statistical minute-by-minute PTCA comparison against a healthy population shows that ischemic patients monitoring reached values of Sensitivity = 99.5% and Specificity = 99.4%, when STVD, TVD and SVG were used in the classification. In conclusion the sensitivity and specificity for acute ischemia monitoring could be increase with the used of only three vectorcardiographic parameters.
Highlights
Myocardial ischemia is caused by a decompensation between the oxygen supply and demand; it is frequently associated with coronary atherosclerosis
These two conventional indexes, here in we examined 4 vectorcardiographic parameters computed in the ST-T interval to further describe cardiac dynamic changes during an episode of acute ischemia induced by Percutaneous Transluminal Coronary Angioplasty (PTCA)
On the basis of the statistical analysis, it can be observed in figure 3 that all the vectorcardiographic parameters
Summary
Myocardial ischemia is caused by a decompensation between the oxygen supply and demand; it is frequently associated with coronary atherosclerosis. Percutaneous Transluminal Coronary Angioplasty (PTCA) is a therapeutic procedure used to reestablish blood flow in narrowed arteries Such procedure provides an attractive opportunity to study myocardial changes due to lack of coronary patency during its initial minutes [1]. Several studies have demonstrated that ventricular depolarization is modified during acute myocardial ischemia induced by PTCA [3,4]. In this context, other conventional index that provides information on the cardiac conduction system operation and on the ventricular action potential duration heterogeneity is the Spatial Ventricular Gradient (SVG) [5]. We evaluated the proposed and the conventional parameters in the classification scheme
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