Analysis of the species composition of the intestinal micro biota in stroke patients: Discovering a new risk factors and screening approaches

Abstract

The human gut contains microbiota, which refers to the collection of microorganisms that inhabit the body. These gut microorganisms can affect the nervous system through the bidirectional communication between the gut and the brain, known as the gut-brain axis. The microbiota can produce various neurotransmitters and signaling molecules that influence the nervous system and the immune system. Alterations in the composition of the gut microbiota, known as dysbiosis, have been associated with neurological disorders such as Parkinson's disease, Alzheimer's disease, and autism spectrum disorders. Maintaining a good and diverse gut microbiota is important for overall health and wellbeing. The composition of the gut microbiota in stroke patients can differ from that of healthy individuals. The emerging evidence suggests that the gut microbiota may play a role in the pathogenesis of stroke and could potentially be a target for therapeutic and preventing interventions. Research is ongoing to fully understand the changes in gut microbiota composition following stroke. Stroke patients have lower levels of beneficial bacterial species, such as Bifidobacterium spp. and Lactobacillus spp., and higher levels of opportunistic bacteria, such as Enterobacteriaceae and Streptococcus spp. The composition of the gut microbiota can differ depending on the type and severity of stroke.