Analysis of the factors affecting hyponatremia in patients with liver cirrhosis

Abstract

Objective To analyze the influencing factors of hyponatremia in patients with liver cirrhosis, and to provide guidance for clinical prevention and treatment of hyponatremia in patients with liver cirrhosis. Methods 200 cases of liver cirrhosis in our hospital from January 2013 to December 2015 were selected as the research object, the clinical data of patients were retrospectively analyzed, the patients were divided into hyponatremia group and normal group according to whether there was hyponatremia or not. Compared the clinical data, analyzed the factors affecting hyponatremia in patients with liver cirrhosis with univariate and multivariate Logistic regression analysis. Results Univariate analysis showed that there were statistically significant differences in the number of cases of age more than 60 years old, excessive diuresis, nausea and vomiting, low sodium diet, excessive limit water, excessive exhaust ascites, gastrointestinal inflammation, abdominal infection, large dose of laxative between hyponatremia group and normal group (56 vs.37, 42 vs.29, 17 vs.9, 34 vs.21, 38 vs.24, 33 vs.24, 21 vs.13, 26 vs.16, 19 vs.11; P<0.05). Multivariate Logistic regression analysis showed that the influencing factors of hyponatremia in patients with liver cirrhosis were age, excessive diuresis, nausea and vomiting, low sodium diet, excessive limit water, excessive exhaust ascites, gastrointestinal inflammation, abdominal infection, large dose of laxative. Conclusion Patients with cirrhosis were easily complicated with hyponatremia, nursing staff should implement targeted nursing intervention measures according to the influencing factors of hyponatremia in patients with liver cirrhosis, to correct the blood sodium level and reduce the incidence of hyponatremia. Key words: Liver cirrhosis; Hyponatremia; Influencing factor