Analysis of gastric myoelectrical and brain waves activity interaction during pre and postprandial

Abstract

Electrogastrogram (EGG) is a well-known method to record gastric myoelectrical activity. However, some researchers believed that EGG measures the gastric slow wave and can be the surrogate of gastric motility, while the others claim that EGG is flawed. Our proposed study extends the EGG study, especially the possibility of observing gut-brain signaling pathways that can improve the understanding of brain properties and its behavior according to the food intakes and other digestion abnormalities. Four subjects participated in this study, and we used a 250 Hz bio amplifier where nineteen channels of EEG to observe brain wave activity were placed on the head scalp. Electrodes were also placed around the stomach to investigate the gastric myoelectrical activity. We applied the FIR filter to obtain each brain wave properties. Also, by employing undersampling and a specific band-pass filter (0.03 - 0.07 Hz), we extracted the power spectrum of the EGG. We found that each subject has different responses during pre and postprandial, both EGG and EEG. The increase of EGG activity caused the deflation of EEG properties, especially in the alpha band. Also, the EEG P3 site at the parietal lobe followed the power change rates of EGG oppositely. We conclude that the relationship between brain waves and gastric myoelectrical activity is possible and needs to be observed in the future.