Abstract
随着广谱抗生素、激素、免疫抑制剂的广泛使用,器官移植术的开展、肿瘤放化疗的增多以及侵袭性操作的日益频繁,获得性免疫缺陷综合征(AIDS)的流行和一些慢性病住院时间延长等因素作用,侵袭性真菌感染的发生率、病死率逐年增加[1],已引起临床医生的重视.据报道器官移植和恶性肿瘤患者中真菌感染的患病率高达20%~40%[2],而且往往是致命的感染.目前临床常规所分离的真菌除白色念珠菌、光滑念珠菌等酵母菌外由曲霉、毛霉、青霉、镰刀菌等丝状真菌所引起的真菌感染日益多见.本研究调查上海交通大学医学院附属仁济医院2009年7月至2010年3月送检的临床标本所分离出的丝状真菌的分布情况,结合患者临床资料分析高危因素与丝状真菌感染的关系。
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