Abstract
Sample preparation is an important step in any biochemical protocol, and several algorithms are known for automating them on a digital microfluidic (DMF) lab-on-a-chip (LoC). On-chip dilution of a sample on a DMF biochip involves several mix-split steps, which often suffer from the inaccuracies caused by unbalanced splitting of micro-fluid droplets. Also, error minimization is essential because of the limited availability of the stock solutions and costly reagents. In this work, we analyze the performance of two dilution algorithms Min-Mix (Thies et al., 2008) and DMRW (Roy et al., 2010) in the presence of volumetric errors that may occur during the splitting process. Our analysis exposes many interesting error behaviors and indicates possible solutions to correct them in a cyber-physical microfluidic platform.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
