Abstract

Background: Cervical cancer is the most common cancers in female population of Nepal. Though considered a slow growing cancer, majority of patients still present very late. 
 Methodology: One hundred patients of cancer cervix were retrospectively analysed to see their spectrum of clinical presentation and care pathway from January 2012 to April 2012. 
 Results: The clinical spectrum showed they presented to clinic after average of 9 months of symptoms. Squamous cell cancers were the main histology. Majority of cases were in FIGO stage of II and IIIB. Radiation therapy with tele-therapy and brachytherapy was the main modality of treatment (94%) of cases. 
 Conclusion: Late stage of presentation is a very common phenomenon in the patients with cancer of cervix. Need screening programs in systematic manner to detect early stage diseases and for better care.

Highlights

  • Cervical cancer is a malignant neoplastic disease that tends to begin slowly when there is a disruption of the cervical epithelium, near the squamo-columnar junction of the uterine cervix

  • This pre-invasive process is limited to the cervical epithelium and is known variably as cervical intraepithelial neoplasia (CIN), according to the classification scheme mostly used in histopathology, or as squamous intraepithelial lesion (SIL), as per the classification system favored for cytopathological diagnosis Low-grade SIL (LSIL) and high grade SIL (HSIL, equivalent to CIN 2 and 3) are invariably asymptomatic and can be detected through cytological examination using the Papanicolaou technique

  • LSIL may become HSIL, and the latter may eventually extend to the full thickness of the cervical epithelium, a condition that is recognized as cervical carcinoma in situ (CIS)

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Summary

Introduction

Cervical cancer is a malignant neoplastic disease that tends to begin slowly when there is a disruption of the cervical epithelium, near the squamo-columnar junction of the uterine cervix. This pre-invasive process is limited to the cervical epithelium and is known variably as cervical intraepithelial neoplasia (CIN), according to the classification scheme mostly used in histopathology, or as squamous intraepithelial lesion (SIL), as per the classification system favored for cytopathological diagnosis Low-grade SIL (LSIL) (equivalent to CIN 1) and high grade SIL (HSIL, equivalent to CIN 2 and 3) are invariably asymptomatic and can be detected through cytological examination using the Papanicolaou technique (the Pap test). Though considered a slow growing cancer, majority of patients still present very late

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