Abstract

<p><strong><span id="page764R_mcid5" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 424.648px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(1.07883);" role="presentation">Introduction</span></span></strong><span id="page764R_mcid6" class="markedContent"><span dir="ltr" style="left: 486.074px; top: 424.648px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.945554);" role="presentation"><strong>.</strong> Detection of early carious lesion and its remineraliza</span></span><span id="page764R_mcid8" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 444.648px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.984641);" role="presentation">tion is the most effective way for caries treatment. The aim of this </span></span><span id="page764R_mcid9" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 464.648px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.930975);" role="presentation">study is to compare effectiveness of remineralization of the early car</span></span><span id="page764R_mcid11" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 484.648px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.944369);" role="presentation">ious lesions with different fluoride varnishes.</span></span></p> <p><span id="page764R_mcid12" class="markedContent"><strong><span dir="ltr" style="left: 392.126px; top: 514.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(1.05127);" role="presentation">Method</span></strong></span><span id="page764R_mcid13" class="markedContent"><span dir="ltr" style="left: 450.559px; top: 514.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.93636);" role="presentation"><strong>. </strong>The research included 30 children, girls and boys, aged 12 </span></span><span id="page764R_mcid14" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 534.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.929762);" role="presentation">and 13, in whom the presence of white lesions on at least two vestib</span></span><span id="page764R_mcid16" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 554.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.963568);" role="presentation">ular surfaces was detected on 60 permanent teeth during a clinical </span></span><span id="page764R_mcid17" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 574.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.925059);" role="presentation">examination by visual method. Gingival status was determined based </span></span><span id="page764R_mcid18" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 594.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.987576);" role="presentation">on bleeding or non-bleeding after probing, activity of the white le</span></span><span id="page764R_mcid20" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 614.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.930098);" role="presentation">sion was visually examined and the size of the lesion was measured. </span></span><span id="page764R_mcid21" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 634.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.952746);" role="presentation">After the measurement, the application of varnishes was performed </span></span><span id="page764R_mcid22" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 654.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.951335);" role="presentation">by the procedure that two different dental varnishes were applied to </span></span><span id="page764R_mcid23" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 674.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.98443);" role="presentation">two different teeth with white lesion in the same person: group I –</span></span><span id="page764R_mcid24" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 694.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.982215);" role="presentation">fluoride varnish with 1.5% non-organic ammonium fluoride, group </span></span><span id="page764R_mcid25" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 714.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.951151);" role="presentation">II – fluoride varnish enriched with minerals with 5% sodium fluoride. </span></span><span id="page764R_mcid26" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 734.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.960597);" role="presentation">Activity, lesion dimensions and gingival status were examined after </span></span><span id="page764R_mcid27" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 754.097px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.934337);" role="presentation">four, eight and twelve weeks when new varnishes were also applied.</span></span></p> <p><span id="page764R_mcid28" class="markedContent"><strong><span dir="ltr" style="left: 392.126px; top: 783.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.964007);" role="presentation">Results</span></strong></span><span id="page764R_mcid29" class="markedContent"><span dir="ltr" style="left: 445.692px; top: 783.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(1.01556);" role="presentation"><strong>.</strong> Inactivation of white lesions was recorded in the eighth </span></span><span id="page764R_mcid30" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 803.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(1.03667);" role="presentation">week, but statistically significant difference was recorded after </span></span><span id="page764R_mcid31" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 823.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.931813);" role="presentation">twelve weeks with 56.2% inactive lesions in the group I and 57.5% in </span></span><span id="page764R_mcid32" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 843.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.925568);" role="presentation">the group II. There was no recorded difference in the lesion activity of </span></span><span id="page764R_mcid33" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 863.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.928553);" role="presentation">the varnishes. Changes in the gingivo-incisal diameter during the vis</span></span><span id="page764R_mcid35" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 883.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.935228);" role="presentation">its amounted to: 3.47 mm/3.59 mm/3.53 mm/3.46 mm for the group I </span></span><span id="page764R_mcid36" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 903.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.921688);" role="presentation">and 3.21 mm/3.19 mm/3.18 mm/3.20 mm for the group II. Changes in </span></span><span id="page764R_mcid37" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 923.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.94927);" role="presentation">mesio-distal diameter amounted to: group I: 2.94 mm/2.81 mm/2.84 </span></span><span id="page764R_mcid38" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 943.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.942486);" role="presentation">mm/2.4 mm; group II: 2.94 mm/2.87 mm/2.89 mm/2.90 mm. Statisti</span></span><span id="page764R_mcid40" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 963.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.955187);" role="presentation">cally significant difference in both diameters was recorded between </span></span><span id="page764R_mcid41" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 983.546px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.910905);" role="presentation">the first and second visit in the group I (p = 0.0046). There was no sta</span></span><span id="page764R_mcid43" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 1003.55px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.982722);" role="presentation">tistically significant difference recorded in the group I during other </span></span><span id="page764R_mcid44" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 1023.55px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.944744);" role="presentation">visits. In the group II statistically significant differences in the chang</span></span><span id="page764R_mcid46" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 1043.55px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.938884);" role="presentation">es of lesion dimension were not recorded. Statistically significant dif</span></span><span id="page764R_mcid48" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 1063.55px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.924091);" role="presentation">ferences p< 0.001 were recorded in the presence of gingival bleeding </span></span><span id="page764R_mcid49" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 1083.55px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.984019);" role="presentation">between the examined groups at the first visit, where significantly </span></span><span id="page764R_mcid50" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 1103.55px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.935549);" role="presentation">more lesions with healthy gingiva were observed in group I (84.4%).</span></span></p> <p><span id="page764R_mcid51" class="markedContent"><strong><span dir="ltr" style="left: 392.126px; top: 1132.99px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.994541);" role="presentation">Conclusion</span></strong></span><span id="page764R_mcid52" class="markedContent"><span dir="ltr" style="left: 474.108px; top: 1132.99px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.921876);" role="presentation"><strong>.</strong> Dental fluoride varnishes cause remineralization of early </span></span><span id="page764R_mcid53" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 1152.99px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.971069);" role="presentation">carious lesion after twelve weeks without significant difference be</span></span><span id="page764R_mcid54" class="markedContent"></span><span id="page764R_mcid55" class="markedContent"><span dir="ltr" style="left: 392.126px; top: 1172.99px; font-size: 16.6667px; font-family: sans-serif; transform: scaleX(0.921841);" role="presentation">tween classic and enriched varnishes.</span></span></p>

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