Abstract

Herein, we present a very rare case of enteropathy-associated T-cell lymphoma (EATL) type 2 with pulmonary metastasis which was biopsy-proven. This is a very rare type of lymphoma, and no case reports or studies of enteropathy-associated T-cell lymphoma with pulmonary metastatic disease were found in the literature review.This 64-year-old male, who presented with an acute abdomen, was found to have a perforation. Subsequent pathology of the resected specimen showed neoplastic cells consistent with EATL type 2. Four months post-diagnosis, the patient developed shortness of breath. Positron emission tomography (PET) scan revealed multiple metabolically active pulmonary nodules. A biopsy of the nodules was consistent with metastatic EATL type 2 involving the lungs.

Highlights

  • Enteropathy-associated T-cell lymphoma (EATL) is a rare peripheral non-Hodgkin's T-cell lymphoma originating from intraepithelial T lymphocytes of the intestines [1]

  • It is very difficult to diagnose the tumor on imaging studies, such as a computerized tomography (CT) scan of the abdomen, as the tumor infiltrates the wall of the intestine and does not present as a mass or growth

  • Our patient presented with intestinal perforation and had evidence of disseminated disease

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Summary

Introduction

Enteropathy-associated T-cell lymphoma (EATL) is a rare peripheral non-Hodgkin's T-cell lymphoma originating from intraepithelial T lymphocytes of the intestines [1]. The patient was a 64-year-old male with a past medical history significant for hypertension, hyperlipidemia, and diabetes mellitus type 2 He presented to the emergency room with severe abdominal pain with an episode of almost passing out at home. He was in his usual state of health and noticed intermittent abdominal pain associated with nausea and vomiting for two to three weeks He was brought to the emergency room where a computerized tomography (CT) scan of the abdomen showed a perforation involving the distal jejunum/proximal Ileum and free air. He underwent exploratory laparotomy and small bowel resection. In view of the poor prognosis, the family chose patient comfort measures only, and he succumbed to his disease

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