An Unusual Association of Mirizzi Syndrome and Cholangiocarcinoma - A Case Report

Abstract

Submit Manuscript | http://medcraveonline.com at the neck of the gall bladder [1] Pablo Luis Mirizzi [2] first described it in 1948 & four types of Mirizzi syndrome have been recognized until now to aid in the appropriate treatment [3]. Symptoms and signs are similar to gall stone causing obstruction with the clinical triad of Fever, Right upper quadrant pain and Obstructive pattern jaundice. The obstruction of the CBD and the obstructive jaundice pattern seen in Mirizzi syndrome is thought to be related to the external compression and fibrotic changes due to the presence of chronic inflammation [4]. A number of reports have been published in the literature showing a clear association between GB carcinoma and Mirizzi syndrome [5,6] however our case describes the presence of Cholangiocarcinoma with this unusual syndrome. The main factor thought to play a key role in the pathogenesis of both these diseases is the presence of chronic biliary inflammation. Our case describes a patient with Mirizzi syndrome, who showed post-operative pathological findings consistent with Cholangiocarcinoma. Case Presentation