Abstract
High performance thin layer chromatography (HPTLC) is a sophisticated instrumental technique based on the full capabilities of thin layer chromatography. The advantages of automation, scanning, full optimization, selective detection principle, minimum sample preparation, hyphenation, etc. enable it to be a powerful analytical tool for chromatographic information of complex mixtures of inorganic, organic, and biomolecules. The chapter highlights related issues such as journey of thin-layer chromatography, basic principle, protocol, separation, resolution, validation process, recent developments, and modifications on TLC leading to the HPTLC, optimization, process control, automation, and hyphenation. It explains that HPTLC has strong potentials as a surrogate chromatographic model for estimating partitioning properties in support of combinatorial chemistry, environmental fate, and health effect studies.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
