Abstract
The design and application of an interstitial light delivery system suitable for photodynamic therapy of liver metastases is presented. The device incorporates an optical portion and a localization portion. Accurate geometric positioning of four 200 μm diameter optical fibres can be achieved and orientated within a metastasis after initial placement of a single fibre using real time ultrasound imaging. The device can either be applied using the percutaneous route or directly into the liver at laparotomy.
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