Abstract
This paper reports on the in vitro assessment of the acid resistance characteristics of mesoporous silica/nanohydroxyapatite (MSN@nHAp) biocomposite synthesized through the mechanochemical method. Bovine enamel models were used to study the acid resistance characteristics of the composite (n=5). X-ray diffraction and Fourier transform infrared spectroscopy were used to characterize the surface morphology of the MSN@nHAp. The XRD and FTIR results confirmed the successful syntheses and surface modification of nanohydroxyapatite with silica. The MSN@nHAp exhibits superior acid resistance characteristics. The salient aspect of this study suggests that mechanochemistry is a useful technique in the synthesis and surface modification of valuable biomaterials. The study concludes that the MSN@nHAp composite could be utilised in toothpaste formulation for oral healthcare management due to its acid resistance properties.
Highlights
Dentin hypersensitivity (DH) is a noticeable dental problem with a negative consequence on the individual’s quality of life [1]
This study was aimed at assessing in vitro the acid resistance characteristics of MSN@nHAp biocomposite synthesized through the mechanochemical method for its potential application in the management of DH
The results obtained from the study indicate that MSN@nHAp was successfully synthesized and modified using the mechanochemical method
Summary
Dentin hypersensitivity (DH) is a noticeable dental problem with a negative consequence on the individual’s quality of life [1]. A novel approach in the treatment and management of DH is the use of various nanomaterials [4, 5]. Among these materials, mesoporous silica (MSN) and nanohydroxyapatite (nHAp) had gained enormous research interest due to their antibacterial action; physical, mechanical, and biological characteristics; and distinctive particle size [6, 7]. Previous studies reported that nHAp could repair tooth enamel [8, 9], which suggests that it might be useful to treat
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