Abstract
BackgroundEndoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) is increasingly utilized to enhance the cytological yield of sampling solid lesions, but its superiority over existing fine-needle aspiration (FNA) platforms has not been clearly demonstrated. The aim of our study was to compare the diagnostic accuracy and procedural outcomes of FNB using a new Franseen-tip needle to that of a traditional FNA in sampling solid lesions under EUS guidance.MethodsConsecutive patients with solid lesions referred for EUS-FNB sampling were included. Procedure-related outcomes were collected prospectively including patient demographics, number of passes performed, diagnostic sample adequacy, adverse events, and recovery time. The Acquire needle was used to sample all lesions in the study group. Consecutive EUS-FNA procedures performed to sample solid lesions using the Expect needle were utilized as controls.ResultsThere were 180 patients undergoing EUS-FNB compared to 183 patients undergoing EUS-FNA procedures for solid-lesion sampling. The procedure time was significantly shorter in patients who underwent FNB compared to FNA (mean: 37.4 vs 44.9 minutes, P < 0.001). Significantly fewer passes were performed in the FNB cohort compared to the FNA group (mean: 2.9 vs 3.8, P < 0.001). The cytologic diagnostic yield was significantly higher in the FNB group compared to the FNA group (98.3% vs 90.2%, P = 0.003). No significant difference in the incidence of adverse events was observed between the FNB and FNA groups (1.1% vs 0.5%, P = 0.564).ConclusionsAn FNB-exclusive approach to sampling solid lesions under EUS guidance is safe and feasible, and may result in fewer overall passes, shorter procedure time, and improved diagnostic adequacy. FNB may replace FNA as the primary sampling modality of choice in all solid lesions.
Highlights
Endoscopic ultrasound-guided fine- needle aspiration (EUSFNA) has been a standard modality used for the diagnosis and staging of gastrointestinal (GI) malignancies and other non-malignant lesions accessible from the GI tract
Most of the patients belonged to American Society of Anesthesiologists (ASA) class 3 (Table 1)
In a study by Aadam et al [11], Endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) was found to have significantly higher diagnostic yield compared with EUS-fine-needle aspiration (FNA), in subgroup analysis, there was no significant difference in the diagnostic yield for pancreatic lesions
Summary
Endoscopic ultrasound-guided fine- needle aspiration (EUSFNA) has been a standard modality used for the diagnosis and staging of gastrointestinal (GI) malignancies and other non-malignant lesions accessible from the GI tract. Endoscopic ultrasound-guided fine- needle biopsy (EUS-FNB) is increasingly being utilized to enhance cytological yield during the sampling of solid lesions [3]. Our study compared the performance of a novel Franseentip biopsy needle to a standard FNA device in sampling solid lesions under EUS guidance. Endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) is increasingly utilized to enhance the cytological yield of sampling solid lesions, but its superiority over existing fine-needle aspiration (FNA) platforms has not been clearly demonstrated. The aim of our study was to compare the diagnostic accuracy and procedural outcomes of FNB using a new Franseen-tip needle to that of a traditional FNA in sampling solid lesions under EUS guidance
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
