Abstract
Surgical site infections (SSIs) are increasing worldwide. The present study demonstrates the efficacy and economic outcome of triclosan-coated sutures (TCS) vs conventional non-antimicrobial-coated sutures (NCS) for SSIs in general surgery in India. A systematic literature search of available evidence for both SSI incidences and TCS efficacy data in India from 1998-2018 and 2000-2018, respectively, were gathered. We collected cost data from a private and public hospital, respectively for hernia and cholecystectomy procedures. The cost-effectiveness of TCS in comparison to the conventional NCS was calculated using a decision-tree deterministic model. We performed a one-way sensitivity analysis to compare TCS vs NCS. We found a base cost saving of INR 9621 (private hospital) and INR 1900 (public hospital). Whereas, for cholecystectomy, it was INR 14450 (private hospital) and INR 2643 (public hospital). The use of TCS resulted in reduced SSI incidence and cost savings for general surgeries in India.
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