An attempt to use the peritoneal cavity fluid in the diagnostics of acid-base balance disorders in dogs

Abstract

The acid-base balance parameters (ABB) of blood are used in the diagnostics and therapy of acidosis or alkalosis type disorders. Nowadays, some reports on the attempts to use the body cavity fluid for the diagnostics of the ABB disorders have appeared in the human medicine. The study has aimed at comparing the acid-base balance parameters (ABB): pH, pCO2, and HCO3(-) determined in the arterial blood and the fluid from the peritoneal cavity in dogs. The study was carried out on 20 dogs suffering from ascites developed as a result of the chronic renal failure. 1 ml of full blood was drawn from each dog from its femoral artery to a heparinized syringe equipped with a needle with an internal diameter of 0.7 mm and the puncture of the abdominal cavity was carried out in the white line. In the sample of arterial blood and the sample of the abdominal cavity fluid drawn the ABB parameters were determined. In the group examined, the ABB parameters determined for the arterial blood and the fluid had comparable numeric values and the same nature of the ABB disorder diagnosed on the basis of them. The conclusions are as follows: the results of the effusion fluid gasometry depend on the mechanism of the fluid formation and, in the case when it comes from the developed capillary network, a pressure of gases and remaining ABB parameters are similar to those determined for the arterial blood.