Abstract
DOPPS 3 shows a high incidence of malignancies in dialysis patients. The main meta-analysis shows a higher IR for cancer than the general population, especially in patients with age <35 years; patients are identified with ESRD-related and other immune deficiency-related malignancies: the former has a RR of 4 in dialysis and renal transplantation, the latter has RR of 1.5 in dialysis but 5 in renal transplantation. The importance of immunosuppression for transplanted patients is stressed. Our experience: we examined 255 patients on chronic dialysis from 2001 to 2009; we identified a case of asymptomatic carcinoid tumor. A 45-year-old woman, underwent gastro-duodenal endoscopy for pre-transplant kidney screening; we detected a duodenal polyp:histological examination showed the presence of cells of medium and uniform size with immunohistochemical reactivity for chromogranin, neuron-specific enolase and synaptophysin. According to guidelines, the patient was suspended for two years from waiting list. Then she repeated diagnostic exams with normal results. Finally she was included in waiting list. We examine the literature regarding carcinoid tumors in patients on chronic dialysis or kidney transplant. We highlight the importance of common diagnostic tests for the prevention of malignancies in patients on chronic dialysis.
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