Abstract
Background Sleep is recognized as an all-important physiological process, which also contributes to maintaining several bodily functions and systems. According to the Pittsburgh Sleep Quality Index (PSQI), also known as the most widely used tool in the field of subjective assessment of self-perceived sleep quality, a combination of acupoints could be more effective than single acupoint treatment in improving sleep quality. Methods The present study was based on the extracted eligible studies rooted in a previous meta-analysis that worked on the basis of association rule mining and examined the potential kernel acupoint combinations for improving sleep quality. Results Depending on the Apriori algorithm, we summarized 26 acupoints as binary data from the 32 eligible studies based on a previous meta-analysis and analyzed them. The top 10 most frequently selected acupoints were HT7, SP6, PC6, KI1, GV20, EM5, EX-HN3, EX-HN16, KI3, and MA-TF1. Furthermore, as deduced from 21 association rules, the primary relevant rules in the combination of acupoints are (EX-HN3, EX-HN16)=>(GV20) and (HT7, KI1)=>(PC6). Conclusions In order to use acupuncture to improve sleep quality, integrating (EX-HN3, EX-HN16, GV20) with (HT7, KI1, PC6) acupoints could be deemed as the kernel acupoint combination.
Highlights
Sleep is recognized as an all-important physiological process, which contributes to maintaining several bodily functions and systems
As stated by the antecedent metaanalysis, 26 acupoints were withdrawn from the 32 retrieved eligible studies. erefore, taking Figure 1 as an example, a barplot was presented to sum up the acupoint frequency distribution. e following 10 acupoints were the most frequently selected among all the acupoints for best effects on sleep disorders and similar symptoms: HT7, SP6, PC6, KI1, GV20, EM5, EX-HN3, EX-HN16, KI3, and MA-TF1
Data for 26 acupoints were recapitulated from acupoint combinations with reference to association rule analysis for the itemset (Table S1). e sporadic plot in Figure 2 demonstrates that all rules have excellent progress. e support/ confidence border can be detected for the optimal rules [30]
Summary
Sleep is recognized as an all-important physiological process, which contributes to maintaining several bodily functions and systems. According to the Pittsburgh Sleep Quality Index (PSQI), known as the most widely used tool in the field of subjective assessment of self-perceived sleep quality, a combination of acupoints could be more effective than single acupoint treatment in improving sleep quality. E present study was based on the extracted eligible studies rooted in a previous meta-analysis that worked on the basis of association rule mining and examined the potential kernel acupoint combinations for improving sleep quality. Depending on the Apriori algorithm, we summarized 26 acupoints as binary data from the 32 eligible studies based on a previous meta-analysis and analyzed them. As deduced from 21 association rules, the primary relevant rules in the combination of acupoints are (EX-HN3, EX-HN16) >(GV20) and (HT7, KI1) >(PC6). In order to use acupuncture to improve sleep quality, integrating (EX-HN3, EX-HN16, GV20) with (HT7, KI1, PC6) acupoints could be deemed as the kernel acupoint combination
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