Abstract
An 131I-labeled iodotamoxifen has been prepared by a “no carrier added” procedure in a 40% radio-chemical yield via an aryl diazonium ion salt intermediate. Two approaches were used to produce high specific activity iodotamoxifen: nonaqueous solvents and copper catalysis. The use of the nonaqueous solvent acetonitrile has proved successful while neither copper powder, copper-bronze, copper(I)oxide nor Cu(II) sulphate showed any catalytic effects.
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Schedule a callMore From: International Journal of Radiation Applications & Instrumentation. Part A, Applied Radiation & Isotopes
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