Abstract
The relationship between the chemical structure and antibacterial activity of alkoxyacetophenone amidinohydrazones was studied. m- or p-Alkoxy compounds showed maximum antibacterial activities with carbon atoms in the alkoxy group, and o-alkoxy compounds with 8-10 carbon atoms. Substitution of -NH2 with -[chemical formula], -[chemical formula] or -[chemical formula] in amidino moiety generally lowered the activity. Antibacterial potency of these compounds against gram-positive bacteria (G+), gram-negative bacteria (G-), and fungi. (F) decreased in this order but compounds having -[chemical formula] or -[chemical formula] at amidino moiety showed the order of G+>F>G-.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
