Ameliorative effect of vitamin E against radiofrequency radiation emitted from mobile phone-induced hematological and histopathological alterations in male albino mice

Abstract

Abstract Radiofrequency radiation is widespread in the surrounding environment and their frequent sources are mobile phones. Consequently, the present research was aimed to study the effect of radiofrequency radiation released from mobile phones on some hematological parameters (RBC, HB, MCV, MCH, MCHC, WBC, P LT, LYM %) and histopathological changes in male white mice. In this work, forty adult male albino mice (25-30 gm weight) divided into four equal groups; A, B, C, and D. Group A was used as a negative control group, Group B used as a negative control group for vitamin E solution, group C was exposed to EMR for 2hr ⁄day for 3 weeks without vitamin E and Group D, treated with Vitamin E solution and exposed to EMR for 2hr ⁄day for 3 weeks. The obtained results revealed that significant changes in RBCs, Hb, HCT, MCV, MCHC, PLT, and WBCs were observed in group C. Additionally, variable histopathological alterations in the liver, kidney, lung, heart, spleen, and brain post-exposure to mobile phone radiation were also demonstrated. Vitamin E has improved these harmful effects induced by radiofrequency radiation on different investigated tissues via their capacity to decline the pathological alterations demonstrated in these organs post-exposure to mobile phone radiation as well as via improving different evaluated blood parameters. Consequently, we could conclude that, vitamin E was able extensively to reduce the harmful influences of mobile phone radiation on blood parameters and the histopathological changes in the liver, kidney, lung, heart, spleen and brain tissues.