Abstract

Quantitative changes in the internal elastic membrane (IEM) were studied in human arteries from different location in 31 males and 31 females, using an eight-criterion classification system. The IEM involvement shows a sex-dependent increase with age, and is more pronounced in arteries known to exhibit a more intensive atherosclerotic involvement. It seems that the IEM changes represent a true ageing phenomenon, which is sometimes influenced to a various degree by the atherosclerotic process.

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