Abstract
Restless Legs Syndrome (RLS) is a neurological disorder whose sufferers demonstrate profound sleep disruption and reduced quality of life. While substantial comorbidities have been noted between RLS and pain conditions such as fibromyalgia, few studies have evaluated potential abnormalities in pain perception in RLS. We evaluated psychophysical responses to noxious thermal and pressure stimuli in both treated and untreated RLS patients, compared to matched controls. Thirty-five RLS patients (20 treated, 15 untreated; 54% female, mean age = 61) were compared to 22 controls with no sleep disorders.
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