Abstract
Age-related macular degeneration (AMD) is a disease leading to severe visual loss and legal blindness in the elderly population overall in cold countries. Its pathogenesis, likely multifactorial, involving a complex and dynamic interaction of metabolic, functional, genetic, and environmental factors, remains poorly understood. For these reasons currently used therapeutic approaches are way beyond to be effective. Two types of AMD are distinguished: the dry and the wet form. Main risk factors include advanced age, genetic predispositions, environmental determinants, history of exposure to intensive light and smoking. Till now, there is no approved therapy for dry AMD, although several agents/treatments are currently in clinical trials. Since upregulated vascular endothelial growth factor (VEGF) is a predominant proangiogenic factor in CNV. the wet AMD can be treated with intra-vitreous application of “anti-VEGF” agents; however, their clinical results are disappointing. In this article, we report clinical results of a novel approach, based in our discovery of the unsuspected intrinsic capacity of human being to transform the power of the sunlight into chemical energy, throughout the dissociation of the water molecule, like plants do it.
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