Abstract
For centuries, it has been clear that fertility declines dramatically as women age beyond their mid-thirties, with only rare pregnancies beyond age 45. In the past 10 years, markers of ovarian reserve in infertile patients have also been shown to strongly influence the potential for pregnancy and have come to guide the approach to diagnosis and treatment. These markers have included assessments of FSH, LH, estradiol, and inhibin in the early follicular (“basal”) phase and after ovarian stimulation (with a clomiphene citrate challenge test or GnRH agonist stimulation test, for example).
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