AFI, SDP and Transvaginal Cervical Length: Parameter of Predictive Delivery Latency in PPROM [21C

Abstract

INTRODUCTION: Prediction of delivery latency complicated with preterm premature rupture of membrane (PPROM) is important for reducing maternal and neonatal complications. However, no studies have correlated parameters including amniotic fluid index, single deepest pocket, transvaginal cervical length, and C-reactive protein as predictive of the latency interval to delivery. We investigated the latency period from PPROM to delivery according to above parameters and predicted delivery latency using cutoff values of these parameters. METHODS: The retrospective study was performed on 121 PPROM patients enrolled between March 2010 and July 2015. Measurements including amniotic fluid index, single deepest pocket, transvaginal cervical length, and C-reactive protein were made in 99 singleton pregnancies with PPROM. Latency was defined as the period from sonographic measurements to delivery day. RESULTS: Gestational age at delivery, body mass index, amniotic fluid index, single deepest pocket, and transvaginal cervical length had significant differences according to delivery latency at 3 days. The median gestational age at delivery, amniotic fluid index, and single deepest pocket were lower, and transvaginal cervical length was significantly shorter in delivery latency within 3 days. Amniotic fluid index and single deepest pocket had the highest sensitivity (82.2%) and single deepest pocket combined with transvaginal cervical length showed the highest specificity (75.9%) and area under curve value. A predicted median latency period was less than 2 days within the cutoff value of parameter. CONCLUSION: Amniotic fluid index and single deepest pocket combined with or without transvaginal cervical length could be useful predictive parameters of the latency period from PPROM to delivery.