Abstract
Interleukin-33 (IL-33) is a new member of the IL-1 family, and ST2 is its specific receptor. In recent years, researches of IL-33/ST2 in autoimmune diseases have drawn extensive interest. IL-33-related autoimmune diseases include rheumatoid arthritis, systemic lupus erythematosus, Sjogren syndrome, systemic sclerosis, psoriasis, inflammatory bowel disease and autoimmune thyroid disease. This article reviews researches on the relationship between IL-33/ST2 and autoimmune diseases. Key words: Interleukins; Receptors, interleukin; Auto immune diseases
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