Abstract
A case of retrovirus-associated adult T-cell lymphoma studied by monoclonal markers and ultrastructure is reported. The patient, who was born in Jamaica and emigrated to Canada 9 years previously, had a 5-year history of asymptomatic lymphocytosis preceding the onset of rapidly progressive disease. The peripheral blood lymphocytes were predominantly pleomorphic small lymphocytes with a smaller population of transformed lymphocytes. The peripheral blood lymphocytes were typed immunologically as T-cells of helper/inducer phenotype. Immunological typing of the lymph node lymphocytes, performed on tissue sections, demonstrated a similar phenotype. Morphological study of the lymph node showed a diffuse lymphoma, encompassing a wide range of cell sizes, including giant cells. In view of the morphological heterogeneity of this condition, immunological and viral studies are recommended to confirm the diagnosis.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
