Abstract
Introduction: In sub-Saharan Africa bacterial meningitis is common and carries a high mortality. Steroid adjuvant therapy has been shown to reduce mortality in adult bacterial meningitis in the developed world but has not been adequately tested in developing countries or in areas of high HIV prevalence. We set out to investigate the use of steroid adjuvant therapy for bacterial meningitis in Blantyre, Malawi where 70% of adult medical inpatients are HIV seroposistive.
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