Abstract

Aversive thresholds were determined by the use of an operant test situation in which rats could control the intensity of an avoidable grid shock. ACTH, dexamethasone, and adrenalin lowered the threshold whereas adrenal demedullation plus dibenzyline raised the threshold. In a second experiment adrenal demedullated rats were deficient in the acquisition of a conditioned emotional response. Results were interpreted to indicate that adrenal activity influenced sensitivity to shock stimulation thereby affecting acquisition of a shock-motivated learning task.

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