Abstract
The response of adrenal hormones and brain catecholamines to immobilization stress, applied in the morning or in the afternoon, was studied in rats. Immobilization induced greater increments in plasma corticosterone in the morning than in the afternoon; i.e. when the basal levels of this hormone were low rather than high. There was no significant difference between the plasma and adrenal corticosterone levels of the morning and those of the afternoon-stressed rats. Decreases in brain norepinephrine were observed in both groups (a.m. and p.m.) of immobilized rats, but no variations in dopamine concentration were detected. Immobilization led to a decline in the adrenal epinephrine level in the morning but no significant variation was observed in the afternoon-stressed rats.
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