Abstract

Chronic pancreatitis (CP) is a persistent inflammation of the pancreas that disrupts normal structure and functions. The absence of well-defined criteria for early diagnosis of CP and the multi-factorial features of the disease render it difficult to develop an effective treatment. Stem cell therapy has emerged as a promising therapy for autoimmune diseases and may represent a therapeutic option for CP treatment. In this issue of Molecular Therapy, Sun et al.1 report that the infusion of adipose-derived mesenchymal stem cells (ASCs) into an experimental murine model of CP inhibited the progression of CP, greatly attenuated pancreatic damage, and reduced fibrosis and cell death.

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