Abstract

Background and Aims: Introduction: Adipokines, expressed by adipose tissue, have been associated with metabolic disturbances and coronary artery disease. Adiponectin has anti-atherogenic and anti-diabetic properties, by inhibiting tumor necrosis factor (TNF)-α. Elevated levels of visfatin and TNF-α are associated with atherosclerosis. Aim: Investigate effects of long-term exercise on circulating levels and adipose tissue expression of adiponectin, visfatin and TNF-α, and explore associations between adiponectin and physical performance, assessed by VO2peak, and glucometabolic variables.

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