Abstract
Adipokine Concentration in Adipose Tissue of Obese Mice: Location Dependency
Highlights
Hypertrophy and hyperplasia of adipocytes leading to enlargement of adipose tissue are the characteristics of obesity
We investigated the differential expression of adipokines from the Subcutaneous Adipose Tissue (SAT), Gonadal Adipose Tissue (GAT) and Perivascular Adipose Tissue (PVAT) of diet-induced obese mice compared with control lean mice
Some studies have shown a positive correlation between adipocyte size and secretion of adipokines from adipocytes, whereas others suggest that the location of adipose tissue is a predominant factor in regulating adipokine secretion [2,3]
Summary
Hypertrophy and hyperplasia of adipocytes leading to enlargement of adipose tissue are the characteristics of obesity. We examined the correlation of adipokine concentrations with the cell-surface area of adipocytes from adipose tissue from three locations. We investigated the levels of different adipokines in SAT, GAT and PVAT in diet-induced obese mice compared with control lean mice.
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