Abstract

More than 300,000 patients are admitted to the hospital each year at a cost of more than $1 billion for treatment of an adhesion-related problem. The most common cause of adhesions is previous surgery, and hernia mesh is one of the inciting causes of adhesions after surgery. Numerous composite or coated prosthetic meshes have been developed to reduce the incidence of adhesion formation after intraperitoneal placement of mesh. Animal studies have documented fewer and less dense adhesions after placement of these meshes; however, no studies in patients have proven that these composite or coated meshes result in fewer adhesion-related complications. Despite the lack of evidence from human studies, because the clinical problem is so prevalent, experimental and theoretical reasons justify use of composite or coated meshes that may reduce the incidence of adhesion formation after intraperitoneal placement of mesh.

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