Abstract

BackgroundPolycystic ovarian syndrome (PCOS) is one of the most prevalent endocrine disorders of women of reproductive age. Treatment plans for this chronic condition frequently include long-term use of a combination of medication and lifestyle interventions. However, treatment outcomes are dependent on adherence to treatment regimens. This study aimed to systematically review the literature for reported adherence to treatments for PCOS.MethodsA systematic search of Embase, Cochrane, PubMed, CINAHL, PsychINFO, SCOPUS, and International Pharmaceutical s from inception until January 2019 utilizing the terms PCOS, adherence, and patient compliance was conducted. A total of 179 possible articles were identified.ResultsFourteen articles reporting adherence data were included in the review. Self-report was the most commonly reported method of measuring adherence. Adherence to lifestyle interventions, such as prescribed diets and physical activity, was reported in ten studies and adherence to medications was reported in seven studies, with some reporting both.ConclusionsMinimal data are available regarding factors associated with adherence in patients with PCOS. Diverse methods of adherence assessment are utilized. Future studies of PCOS treatments should effectively assess and report adherence data as it is essential to evaluating the effectiveness of PCOS treatments and is critically needed to guide clinician efforts to facilitate optimal outcomes for patients.

Highlights

  • Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of reproductiveaged females, impacting 6 to 10% of women.[1]

  • Adherence to lifestyle interventions, such as prescribed diets and physical activity, was reported in ten studies and adherence to medications was reported in seven studies, with some reporting both

  • Minimal data are available regarding factors associated with adherence in patients with Polycystic ovarian syndrome (PCOS)

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Summary

Introduction

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of reproductiveaged females, impacting 6 to 10% of women.[1] Much attention has been given to the need for careful clinical assessment for diagnosis to develop an optimal treatment approach, with treatment modalities including medication and lifestyle management.[2] Treatment goals address a variety of symptoms from reproductive function to hirsutism and acne, as well as commonly associated issues such as insulin resistance. Polycystic ovarian syndrome (PCOS) is one of the most prevalent endocrine disorders of women of reproductive age. Treatment plans for this chronic condition frequently include long-term use of a combination of medication and lifestyle interventions.

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