Abstract
Adenomatoid odontogenic tumor (AOT) is always a benign tumor with rare incidence of recurrence while ameloblastoma is the commonest gnathic tumor, which is always aggressive. Although co-occurrence of these lesions has been reported, this paper describes a homogenous combination of <em>atypical</em> AOT and ameloblastomatous proliferation with some malignant microscopic features. To date, A dozen cases or slightly more of this uncommon composite odontogenic tumor have been, quite correctly, reported in the literature under the designation of <em>adenoid ameloblastoma</em>. Of these, neither cellular atypia nor pleomorphism has been revealed. This extremely rare ameloblastomatous variant can pose a significant diagnostic challenge. Moreover, there were some findings of severe nuclear vacuolization, mitotic figures, cellular pleomorphism and nuclear hyperchromatism and chromatin peripheralization. However, the scattered occurrence of these was not sufficient for claiming a malignancy. To confirm, two immunohistochemical markers - Calretinin and p53 - were recruited. Rendering itself to be suspicious, a rapt attention should be paid toward well interrogating this lesion histologically and immunohistochemically.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.